We present a one per cent measurement of the cosmic distance scale from the detections of the baryon acoustic oscillations in the clustering of galaxies from the Baryon Oscillation Spectroscopic Survey, which is part of the Sloan Digital Sky Survey III. Our results come from the Data Release 11 sample, containing nearly one million galaxies and covering approximately 8500 square degrees and the redshift range 0.2 < z < 0.7. We also compare these results with those from the publicly released (...) DR9 and DR10 samples. Assuming a concordance Λ cold dark matter cosmological model, the DR11 sample covers a volume of 13 Gpc3 and is the largest region of the Universe ever surveyed at this density. We measure the correlation function and power spectrum, including density-field reconstruction of the BAO feature. The acoustic features are detected at a significance of over 7σ in both the correlation function and power spectrum. Fitting for the position of the acoustic features measures the distance relative to the sound horizon at the drag epoch, rd, which has a value of rd,fid = 149.28 Mpc in our fiducial cosmology. We find DV = at z = 0.32 and DV = at z = 0.57. At 1.0 per cent, this latter measure is the most precise distance constraint ever obtained from a galaxy survey. Separating the clustering along and transverse to the line of sight yields measurements at z = 0.57 of DA = and H =. Our measurements of the distance scale are in good agreement with previous BAO measurements and with the predictions from cosmic microwave background data for a spatially flat CDM model with a cosmological constant. © 2014 The Author Published by Oxford University Press on behalf of the Royal Astronomical Society. (shrink)

A variety of commentators have explored the similarities between pragmatism and Thomas Reid’s Philosophy of Common Sense. Peirce himself claims his version of pragmatism either (loosely) is, or entails, a Critical Common-sensism, a blend of what is best in Kant and Reid. In this paper I argue for a neglected aspect of the relation between Peirce and Reid, and of each to common sense: linguistics. First, I summarize Peirce’s account of what distinguishes his common-sensism from Reid’s. (...) Second, I argue for the importance of appeals to linguistic universals by Reid as both a source for identifying common sense beliefs, and a basis for justifying them. While Peirce is occasionally tempted by such appeals, overall he is critical of appeals to language, especially as most Western philosophers have been familiar with a small set of (Indo-)European languages; say, English, French, German, Greek, Italian, and Latin. This leads to the third section, which concerns Peirce’s familiarity with major nineteenth century linguists, and his contention that the ‘peculiarity’ of Western European languages has impeded the development of logic and philosophy. In particular, I look at unpublished manuscripts where Peirce summarizes his own study of non-European languages, ranging from Arabic, to Ngarrindjeri, to Xhosa. Peirce was only an amateur linguist, and also aware of the challenges of doing cross-cultural linguistics through comparative grammar; e.g., the temptation to force unfamiliar languages onto the “Procrustean Bed of Aryan grammar” (CP 2.211). Nonetheless, this study left him suspicious of any claims of linguistic universals, and supported his anti-psychologism. That is, not only should logic and philosophy not be based upon psychology (at least as a special science), they should also be independent of linguistics. However, Peirce also advances something like the so-called Sapir-Whorf hypothesis, that language determines, or at least conditions, thought. The question now becomes what is the nature of a philosophy of common sense, even a critical one, without a common language, or possibly no commonalities across languages? (shrink)

THE QUESTION TO BE CONSIDERED is the relation of Hume's celebrated scepticism to his own constructive philosophical projects and analyses. Since Thomas Reid there have been those who detect an unresolved tension between, on the one hand, Hume's Enlightenment devotion to science with its attendent opposition to dogmatism and superstition and, on the other, his explicitly sceptical manner and principles. Some (e.g., Green and Kolakowski) find this tension unresolvable in principle and utterly subversive of Hume's positive ambitions; others (e.g., (...) Flew and Passmore) propose revisionary interpretations of Hume that will mitigate the tension. Still others adopt the view made popular by Kemp Smith and Hendel, according to which the special virtue of Hume's philosophy is precisely his employment of the principle of "natural interpretation" to overcome the apparent conflict between science and scepticism. The reading of Hume proposed here fits comfortably into none of the traditions, largely because of the emphasis placed upon the changes, both in the character of Hume's scepticism and, more fundamentally, in his own conception of his philosophical project. I shall argue: that Hume began his study of human nature with reformist aspirations toward an accurate and serf-evident "science of man"; that the critical method adopted in pursuit of this goal occasioned corrosive doubts concerning the very possibility of science; that reflection upon the failure of his initial effort led Hume to replace his earlier scientific ideal with a less rigorous program of "natural, unforced interpretation"; that this new "academical philosophy" succeeded neither in providing workable criteria for distinguishing justifiable belief from superstition nor in avoiding the excesses of unmitigated scepticism; and, finally, that there is evidence that Hume was aware of and tacitly conceded these difficulties. (shrink)

The Giving Voice to Values pedagogy and curriculum is described as an example of a powerful leverage point in the integration of business ethics and values-driven leadership across the business curriculum. GVV is post-decision-making in that it identifies an ethical course of action and asks practitioners to identify who are the parties involved and what’s at stake for them; what are the main arguments to be countered; and what levers that can be used to influence those who are in disagreement. (...) The internalization of GVV’s constructs allows faculty to comfortably raise and endorse ethics as part of the natural order of business decision-making because the stakes of doing so have been normalized. Methods for introducing and using GVV in undergraduate through MBA courses are given. An illustration is given for economics courses. (shrink)

This study examines the deliberations of professional MBA students when presented with a dilemma that weighs the difference between commitments to profit-maximization against concerns for fired workers who would need to seek a new job during a recession. Using content analysis, accounting, economic, and ethically based rationales that differ from the profit-maximizing recommendation are categorized. Results also show that those who make non-profit-maximizing recommendations consider, but ultimately reject the profit-maximizing approach to layoffs.

This paper describes KRL, a Knowledge Representation Language designed for use in understander systems. It outlines both the general concepts which underlie our research and the details of KRL‐0, an experimental implementation of some of these concepts. KRL is an attempt to integrate procedural knowledge with a broad base of declarative forms. These forms provide a variety of ways to express the logical structure of the knowledge, in order to give flexibility in associating procedures (for memory and reasoning) with specific (...) pieces of knowledge, and to control the relative accessibility of different facts and descriptions. The formalism for declarative knowledge is based on structured conceptual objects with associated descriptions. These objects form a network of memory units with several different sorts of linkages, each having well‐specified implications for the retrieval process. Procedures can be associated directly with the internal structure of a conceptual object. This procedurul attachment allows the steps for a particular operation to be determined by characteristics of the specific entities involved.The control structure of KRL is based on the belief that the next generation of intelligent programs will integrate data‐directed and goal‐directed processing by using multiprocessing. It provides for a priority‐ordered multiprocess agenda with explicit (user‐provided) strategies for scheduling and resource allocation. It provides procedure directories which operate along with process frameworks to allow procedural parameterization of the fundamental system processes for building, comparing, and retrieving memory structures. Future development of KRL will include integrating procedure definition with the descriptive formalism. (shrink)

I argue against the tendency in the philosophy of science literature to link abduction to the inference to the best explanation (IBE), and in particular, to claim that Peireean abduction is a conceptual predecessor to IBE. This is not to discount either abduction or IBE. Rather the purpose of this paper is to clarify the relation between Peireean abduction and IBE in accounting for ampliative inference in science. This paper aims at a proper classification—not justification—of types of scientific reasoning. In (...) particular, I claim that Peireean abduction is an in-depth account of the process of generating explanatory hypotheses, while IBE, at least in Peter Lipton's thorough treatment, is a more encompassing account of the processes both of generating and of evaluating scientific hypotheses. There is then a two-fold problem with the claim that abduction is IBE. On the one hand, it conflates abduction and induction, which are two distinct forms of logical inference, with two distinct aims, as shown by Charles S. Peirce; on the other hand it lacks a clear sense of the full scope of IBE as an account of scientific inference. (shrink)

[Correction Notice: An erratum for this article was reported in Vol 109 of Psychological Review. Due to circumstances that were beyond the control of the authors, the studies reported in "Models of Ecological Rationality: The Recognition Heuristic," by Daniel G. Goldstein and Gerd Gigerenzer overlap with studies reported in "The Recognition Heuristic: How Ignorance Makes Us Smart," by the same authors and with studies reported in "Inference From Ignorance: The Recognition Heuristic". In addition, Figure 3 in the Psychological Review (...) article was originally published in the book chapter and should have carried a note saying that it was used by permission of Oxford University Press.] One view of heuristics is that they are imperfect versions of optimal statistical procedures considered too complicated for ordinary minds to carry out. In contrast, the authors consider heuristics to be adaptive strategies that evolved in tandem with fundamental psychological mechanisms. The recognition heuristic, arguably the most frugal of all heuristics, makes inferences from patterns of missing knowledge. This heuristic exploits a fundamental adaptation of many organisms: the vast, sensitive, and reliable capacity for recognition. The authors specify the conditions under which the recognition heuristic is successful and when it leads to the counter-intuitive less-is-more effect in which less knowledge is better than more for making accurate inferences. (shrink)

Two institutions that are often implicit or overlooked in noncooperative games are the assumption of Nash behavior to solve a game, and the ability to correlate strategies. We consider two behavioral paradoxes; one in which maximin behavior rules out all Nash equilibria (‘Chicken’), and another in which minimax supergame behavior leads to an ‘inefficient’ outcome in comparison to the unique stage game equilibrium (asymmetric ‘Deadlock’). Nash outcomes are achieved in both paradoxes by allowing for correlated strategies, even when individual behavior (...) remains minimax or maximin. However, the interpretation of correlation as a public institution differs for each case. (shrink)

Giving Voice To Values (GVV) serves as a framework to teach individuals methods to speak up when they witness actions that are contrary to their professional and personal values. This essay illustrates how GVV serves as a catalyst to advance both research and teaching activities.

We experimentally assess the ethics of the U.S. government’s indirect bailout of the bank counterparties of American International Group during the 2008 financial crisis. When the indirect bailout is jointly compared with a counterfactual where the government directly bails out the banks, subjects judge the indirect bailout to be far more unethical. On the other hand, when the two scenarios are judged separately, subjects consider a direct bailout of banks to be more unethical. This suggests that ethical judgments of indirect (...) versus direct action exhibit a type of preference reversal that is dependent upon whether the evaluation mode is joint or separate. The pedagogical and policy implications of this preference reversal are discussed. (shrink)

We have synthesized a 582,970-base pair Mycoplasma genitalium genome. This synthetic genome, named M. genitalium JCVI-1.0, contains all the genes of wild-type M. genitalium G37 except MG408, which was disrupted by an antibiotic marker to block pathogenicity and to allow for selection. To identify the genome as synthetic, we inserted "watermarks" at intergenic sites known to tolerate transposon insertions. Overlapping "cassettes" of 5 to 7 kilobases (kb), assembled from chemically synthesized oligonucleotides, were joined by in vitro recombination to produce intermediate (...) assemblies of approximately 24 kb, 72 kb ("1/8 genome"), and 144 kb ("1/4 genome"), which were all cloned as bacterial artificial chromosomes in Escherichia coli. Most of these intermediate clones were sequenced, and clones of all four 1/4 genomes with the correct sequence were identified. The complete synthetic genome was assembled by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae, then isolated and sequenced. A clone with the correct sequence was identified. The methods described here will be generally useful for constructing large DNA molecules from chemically synthesized pieces and also from combinations of natural and synthetic DNA segments. 10.1126/science.1151721. (shrink)

This paper aims to position the birth of the Medical Humanities movement in a greater historical context of twentieth century American medical education and to paint a picture of the current landscape of the Medical Humanities in medical training. It first sheds light on the model of medical education put forth by Abraham Flexner through the publishing of the 1910 Flexner Report, which set the stage for defining physicians as experimentalists and rooting the profession in research institutions. While this paved (...) the way for medical advancements, it came at the cost of producing a patriarchal approach to medical practice. By the late 1960s, the public persona of the profession was thus devoid of humanism. This catalyzed the birth of the Medical Humanities movement that helped lay the framework for what has perpetuated as the ongoing incorporation of humanistic subjects into medical training. As we enter a time in medicine in which rates of burnout are ever-increasing and there are growing concerns about a concomitant reduction in empathy among trainees, the need for instilling humanism remains important. We must consequently continue to consider how to ensure the place of the Medical Humanities in medical education moving forward. (shrink)

There is a fairly long-standing distinction between what are called the ideographic as opposed to nomothetic sciences. The nomothetic sciences, such as physics, offer explanations in terms of the laws and regular operations of nature. The ideographic sciences, such as natural history, cast explanations in terms of narratives. This article offers an account of what is involved in offering an explanatory narrative in the historical sciences. I argue that narrative explanations involve two chief components: a possibility space and an explanatory (...) causal mechanism. (shrink)

The 1980s witnessed a dramatic increase in hostile takeovers in the United States. Proponents argue that well- planned mergers enhance the value of the firm and the value of the firm to society. Critics typically argue that undesired takeovers ultimately harm society due to external costs not borne by the acquiring firm. To be socially responsible, the manager must consider the effects of the merger/acquisition on all stakeholders. Different traditional ethical frameworks for decision making are proposed and reviewed. A model (...) is proposed. (shrink)

: C.S. Peirce defines mathematics in two ways: first as "the science which draws necessary conclusions," and second as "the study of what is true of hypothetical states of things" (CP 4.227–244). Given the dual definition, Peirce notes, a question arises: Should we exclude the work of poietic hypothesis-making from the domain of pure mathematical reasoning? (CP 4.238). This paper examines Peirce's answer to the question. Some commentators hold that for Peirce the framing of mathematical hypotheses requires poietic genius but (...) is not scientific work. I propose, to the contrary, that although Peirce occasionally seems to exclude the poietic creation of hypotheses altogether from pure mathematical reasoning, Peirce's position is rather that the creation of mathematical hypotheses is poietic, but it is not merely poietic, and accordingly, that hypothesis-framing is part of mathematical reasoning that involves an element of poiesis but is not merely poietic either. Scientific considerations also inhere in the process of hypothesis-making, without excluding the poietic element. In the end, I propose that hypothesis-making in mathematics stands between artistic and scientific poietic creativity with respect to imaginative freedom from logical and actual constraints upon reasoning. (shrink)

In this paper I explore the relationship between the production and the value of Big Data. In particular I examine the concept of social media ‘prosumption’—which has predominantly been theorized from a Marxist, political economic perspective—to consider what other forms of value Big Data have, imbricated with their often speculative economic value. I take the example of social media firms in their early stages of operation to suggest that, since these firms do not necessarily generate revenue, data collected through user (...) contributions do not always realize economic value, at least in a Marxist sense, and that, in addition to their speculative value, these data have value beyond an economic valence. Instead I argue that in addition to their function as systems for accumulation, social media and their associated data have an affective value, related closely to their economic value, and demonstrate the efficacy of social media as systems designed for the appropriation and circulation of user attention. (shrink)

Two institutions that are often implicit or overlooked in noncooperative games are the assumption of Nash behavior to solve a game, and the ability to correlate strategies. We consider two behavioral paradoxes; one in which maximin behavior rules out all Nash equilibria (‘Chicken’), and another in which minimax supergame behavior leads to an ‘inefficient’ outcome in comparison to the unique stage game equilibrium (asymmetric ‘Deadlock’). Nash outcomes are achieved in both paradoxes by allowing for correlated strategies, even when individual behavior (...) remains minimax or maximin. However, the interpretation of correlation as a public institution differs for each case. (shrink)

The α‐actinins are an ancient family of actin‐binding proteins that play structural and regulatory roles in cytoskeletal organisation and muscle contraction. α‐actinin‐3 is the most‐highly specialised of the four mammalian α‐actinins, with its expression restricted largely to fast glycolytic fibres in skeletal muscle. Intriguingly, a significant proportion (∼18%) of the human population is totally deficient in α‐actinin‐3 due to homozygosity for a premature stop codon polymorphism (R577X) in the ACTN3 gene. Recent work in our laboratory has revealed a strong association (...) between R577X genotype and performance in a variety of athletic endeavours. We are currently exploring the function and evolutionary history of the ACTN3 gene and other α‐actinin family members. The α‐actinin family provides a fascinating case study in molecular evolution, illustrating phenomena such as functional redundancy in duplicate genes, the evolution of protein function, and the action of natural selection during recent human evolution. BioEssays 26:786–795, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

This paper gives prescriptions for introducing ethical concerns into the economic theory of the firm. Topics include social responsibility, corporate governance, profit maximization, competition barriers, collusion, the market system, and welfare economics. The need for such prescriptions is based on a content analysis of 21 managerial economics texts for their coverage of ethics. My analysis finds that substantive discussions of ethics are conspicuous by their absence. As ethical breaches can involve significant monetary damages to a firm - particularly through adverse (...) market reactions - moral-reasoning abilities can complement analytical skills. Consequently, my analysis demonstrates how ethics figure into the opportunity costs of managerial decision making, which is central to the economic definition of profit. (shrink)

Henry David Thoreau’s discussion of the highest value of wild apples and my own reflection upon my experience, interacting with the sea and enjoying its products during my Central American upbringing, motivate this discussion of how human beings may apprehend nature’s highest worth. I propose that in order to apprehend nature’s highest value it is necessary to understand the complete transaction between human beings and nature—an active transaction that requires from the human being a continuous movement along experience, reflection, and (...) responsible action. I argue that the economic valuation of natural products—via the contemporary economic concepts of utility, use-value, existence-value, and willingness-to-pay—is insufficient to comprehend the full worth of nature because it reduces the human being-nature transaction to mere economic terms. Hence, a reading of Ralph Waldo Emerson’s Nature provides insight into the services—commodity, beauty, language, and discipline—that the human being receives, as part of the transaction, from nature. In turn, a reading of Aldo Leopold’s A Sand County Almanac complements the Emersonian position by considering the human being’s position as a member of a natural community. Finally, I propose that in order to apprehend the worth of nature, it is further necessary to move from the reflective understanding of the human being-nature transaction into necessary action, that is, into the assumption of responsibility towards nature. (shrink)

in two letters concerning the Spanish-American War of 1898, Charles Sanders Peirce openly expresses some egregious prejudices against several groups of people, including Hispanics—people of at least partly Spanish origin in the Iberian Peninsula or the Americas (L 254 and L 339; reprint, translation to Spanish, and commentary in Nubiola and Zalamea 76–811). In an undated letter to his cousin Henry Cabot Lodge, a Massachusetts politician, Peirce writes regarding the war: “I don’t believe the Spaniards will make a good fight; (...) for as I have studied them in Spain, the whole people has been corrupted with the centuries of cruelty, injustice and rapine they have indulged in, and have little real manhood left” (L 254; .. (shrink)

During an emergency, laws serve crucial functions, including clarifying responsibilities, authorizing critical interventions, and protecting vulnerable populations. However, provisions of existing laws designed for normal, non-emergency circumstances may sometimes hinder emergency response efforts, thereby potentially endangering the public's health rather than protecting it. Pursuant to declared states of emergency, disaster, or public health emergency, however, the legal landscape changes in several important ways. Interventions not legally permissible under non-emergency circumstances become available. One key example is authority to temporarily waive legal (...) provisions that may impede emergency response efforts, such as professional licensing requirements, facility capacity limitations, pharmaceutical pedigree obligations, and state contract restrictions, among other laws spanning a host of legal spheres.This article examines the structure and use of waiver authority in emergencies. It provides recent examples of waivers and analyzes potential application to a hypothetical emergency scenario. (shrink)

The aim of this work is threefold. First, it is an attempt to revisit the doctrine of God’s general revelation in conversation of dogmatic and biblical theology. Beyond the classical twofold categorizations of revelation, as natural and supernatural or general and special, in this work we argue for a threefold understanding of God’s general revelation: revelation in history, revelation in conscience and revelation in creation. Second, we intend to affirm that the foundation for this threefold conception of general revelation is (...) the doctrine of the Trinity and the perichoretic relationships between the three divine Persons in internal life of the Trinity as well as in their activity in creation and salvation. Therefore, history is a space of the Triune God’s revelation, the revelation in conscience is a trinitarian activity, and revelation in creation is unfolding the Father, who creates through the Son in the Spirit. Third, we aim to affirm that there could be possible to elaborate a perichoretic model of God’s general revelation. Being rooted in the perichoretic understanding of Trinity, such a model pressuposes the fact that the three forms of God’s general revelation are indisolubly connected, without contradiction, separation or confusion. (shrink)

Used appropriately, reliance on science distinguishes public health from policymaking driven more by theory and opinion and enhances trust in public health interventions. Evidence-based vaccine policymaking aims to control communicable disease by urging decision makers to base policies on the best available evidence rather than politics or personal views. The results of this approach, such as smallpox eradication, have been dramatic. Historically, mandatory childhood vaccination has been perhaps the most successful evidence-based tool in combating many epidemics. Philosophically, vaccination mandates correspond (...) to the legal system’s dual role in codifying what society deems undesirable behavior and declaring beneficial social norms and values consistent with understandings of the social contract. Despite their effectiveness and philosophical grounding, vaccination mandates present serious legal and ethical questions. Public health policymakers have a continuing responsibility to rely on evidence not only as a basis for generating policy, but also for evaluating and improving elements of its legal design. (shrink)